Actively Recruiting
Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy
Led by Minia University · Updated on 2026-01-21
90
Participants Needed
1
Research Sites
117 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a monocentric, prospective, randomized controlled trial comparing the safety and efficacy of laparoscopic pancreaticoduodenectomy (LPD) versus open pancreaticoduodenectomy (OPD). The study aims to determine the morbimortality of the laparoscopic approach compared to the gold standard open approach in adult patients with pancreatic or periampullary lesions.
CONDITIONS
Official Title
Outcomes After Laparoscopic Versus Open Pancreaticoduodenectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Histologically confirmed or clinically suspected lesions of pancreatic head adenocarcinoma, ampullary carcinoma, distal cholangiocarcinoma, duodenal adenocarcinoma, pancreatic neuroendocrine tumors, or intraductal papillary mucinous neoplasm (IPMN)
- Resectable disease based on preoperative imaging
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2
- American Society of Anesthesiologists (ASA) classification I to III
- Ability to provide informed consent
You will not qualify if you...
- Emergency surgery
- Previous pancreatic surgery
- Concurrent major abdominal procedures
- ASA classification IV or higher
- Metastatic disease identified before surgery
- Locally advanced unresectable disease
- Active infection or sepsis at time of surgery
- Severe cardiopulmonary comorbidities preventing major surgery
- Pregnancy
- Procedures requiring total pancreatectomy, distal pancreatectomy, or enucleation
AI-Screening
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Trial Site Locations
Total: 1 location
1
Liver and GIT hospital , Minia University
Minya, Minya Governorate, Egypt, 61519
Actively Recruiting
Research Team
S
Saleh K Saleh, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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