Actively Recruiting
Outcomes of Children in Whom a Prenatal Exome Was Performed Based on Ultrasound Findings
Led by University Hospital, Strasbourg, France · Updated on 2026-01-15
70
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Amniocentesis is a test offered to couples based on ultrasound findings during pregnancy. Currently, genetic analysis using FISH and ACPA is routinely performed. For the past four years, additional exome sequencing has been offered after two ultrasound findings, if FISH and ACPA are negative. In this study, investigators aim to review the results of this exome sequencing analysis, examine the outcomes obtained, and study the outcomes of the children after birth. Can parents be completely reassured when the exome sequencing is negative, or does this indicate that investigators are not yet sufficiently sensitive in their genetic analysis?
CONDITIONS
Official Title
Outcomes of Children in Whom a Prenatal Exome Was Performed Based on Ultrasound Findings
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Child under 4 years of age
- Exome sequencing performed at the Strasbourg University Hospitals following amniocentesis during pregnancy between November 2021 and September 2025.
You will not qualify if you...
- Refusal to participate in the study
- Exome sequencing not performed at the Strasbourg University Hospital
- Lack of prenatal ultrasound information
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Service de Gynécologique et d'Obstétrique - CHU de Strasbourg - France
Strasbourg, France, 67091
Actively Recruiting
Research Team
C
Chris MINELLA, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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