Actively Recruiting
Outcomes and Cosmesis With Whole Breast Irradiation and Boost
Led by University of Wisconsin, Madison · Updated on 2025-10-23
50
Participants Needed
1
Research Sites
406 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being done to evaluate cosmetic, patient-reported outcome measures (PROMs), and toxicities for women undergoing ultra-short whole breast irradiation (WBI) therapy with simultaneous integrated boost (SIB). 50 participants will be on study for up to 60 months.
CONDITIONS
Official Title
Outcomes and Cosmesis With Whole Breast Irradiation and Boost
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ability to understand and the willingness to sign a written informed consent document
- Histologically confirmed early stage (stage T1-T2) invasive carcinoma of the breast or DCIS
- Breast conserving surgery with negative margins and negative nodes (surgical axillary staging not mandatory), stage N0 or Nx
- Treatment plan should include breast conserving surgery and adjuvant whole breast irradiation (WBI) therapy delivered with 3D-CRT or IMRT techniques
- Treatment plan includes breast tumor bed boost
- Willingness to comply with all study procedures and be available for the duration of the study
You will not qualify if you...
- Mastectomy of ipsilateral breast
- Lack of histologic diagnosis
- Histologic involvement of the axillary or regional nodes or metastatic disease
- Accelerated partial breast irradiation treatment plan
- Previous history of non-breast malignancy diagnosed in the past 5 years except for basal or squamous cell cancer of the skin
- Previous history of chest radiation therapy
- Previous history of ipsilateral breast cancer
- Concurrent cytotoxic chemotherapy
- Active connective tissue disease including scleroderma
- Inability or unwillingness to return for required follow up visit
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
UW Carbone Cancer Center
Madison, Wisconsin, United States, 53792
Actively Recruiting
Research Team
C
Cancer Connect
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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