Actively Recruiting
Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
Led by Krunal Patel · Updated on 2026-02-20
500
Participants Needed
1
Research Sites
782 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to see if stool transplant performed by colonoscopy is effective at treating recurrent Clostridium difficile (C. diff) infection of the colon. During the procedure a stool sample is taken from a healthy donor (usually family member or close friend) and transplanted directly into the colon of the patient with C. diff infection. The goal of this experimental procedure (called fecal microbiota transplantation) is to replenish the good bacteria in the colon that can help prevent C. diff infection from coming back after treatment.
CONDITIONS
Official Title
Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium Difficile
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Two or more recurrences of C. difficile infection with positive test and symptoms within 2-8 weeks of last episode
- Failed standard therapy with oral metronidazole and/or oral vancomycin
- One or more episodes of severe C. difficile infection requiring hospitalization not responding to standard antibiotic therapy
You will not qualify if you...
- Age under 16 years
- Patients with acute severe colonic dilation at risk for colonic perforation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
UMass Memorial Medical Center
Worcester, Massachusetts, United States, 01655
Actively Recruiting
Research Team
A
Anne Foley
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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