Actively Recruiting
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of Intraoperative Incision Wound in Preventing Surgical Site Infections in Emergency Laparotomies: A Randomized Controlled Trial
Led by Dow University of Health Sciences · Updated on 2025-06-18
200
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
CONDITIONS
Brief Title
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
Who Can Participate
Eligibility Criteria
You may qualify if you...
-
• Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi
- The age of patients should be between 18-60 years old.
You will not qualify if you...
- Diabetic patients
- Immune-suppressed patients
- Patients taking steroids
- Patients undergoing chemo-radiotherapy.
- Pregnant females
- Previous abdominal surgery within the last 30 days.
- Presence of concurrent abdominal wall infections.
- Trauma Laparotomies
- Large Bowel perforations
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Trial Site Locations
Total: 1 location
1
Dr. Ruth K. M. Pfau Civil Hospital Karachi
Karachi, Sindh, Pakistan, 74400
Actively Recruiting
Research Team
O
Omer Bin Khalid, Assist Prof.
A
Afeera Ahmed, Undergraduate
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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