Comparing High-Volume Saline Irrigation Versus Povidone-Iodine Cleaning to Prevent Surgical Site Infections in Emergency Laparotomy Patients

What this Trial Is About

This trial investigates surgical site infection prevention in patients undergoing emergency laparotomies. It compares outcomes of high-volume saline irrigation versus povidone-iodine solution cleaning of the incision wound. The main focus is to evaluate the incidence of superficial surgical site infections and the length of hospital stay after surgery. Participants are randomly assigned to one of two groups. Group A receives intraoperative wound irrigation with three rounds of 1 liter of 0.9% saline solution before the incision is closed. Group B undergoes conventional wound closure with no irrigation, but the wound is cleaned with a povidone-iodine swab. The study is conducted in a randomized, triple-blinded manner to compare the effectiveness of these interventions. During the study, participants are monitored for up to 4 weeks post-operatively to measure superficial surgical site infections and hospital stay length. Researchers will collect data on infection rates and recovery time to assess which method better prevents infections following emergency laparotomy. The trial is sponsored by Dow University of Health Sciences and includes adults aged 18 to 60 years.

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies