Actively Recruiting
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
Led by Dow University of Health Sciences · Updated on 2025-06-18
200
Participants Needed
1
Research Sites
139 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
CONDITIONS
Official Title
Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi
- Age between 18 and 60 years old
You will not qualify if you...
- Diabetic patients
- Immune-suppressed patients
- Patients taking steroids
- Patients undergoing chemo-radiotherapy
- Pregnant females
- Previous abdominal surgery within the last 30 days
- Presence of concurrent abdominal wall infections
- Trauma laparotomies
- Large bowel perforations
AI-Screening
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Trial Site Locations
Total: 1 location
1
Dr. Ruth K. M. Pfau Civil Hospital Karachi
Karachi, Sindh, Pakistan, 74400
Actively Recruiting
Research Team
O
Omer Bin Khalid, Assist Prof.
CONTACT
A
Afeera Ahmed, Undergraduate
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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