Actively Recruiting
Outcomes of the PLHIV With Suboptimal Viral Suppression to Injectable Long-acting Antiretrovirals
Led by Chang Gung Memorial Hospital · Updated on 2024-08-23
40
Participants Needed
4
Research Sites
127 weeks
Total Duration
On this page
Sponsors
C
Chang Gung Memorial Hospital
Lead Sponsor
T
Taoyuan General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to determine whether people living with HIV (PLHIV) with suboptimal medical adherence can achieve better viral suppression with long-acting antiretrovirals (LA) compared to all-oral antiretrovirals.
CONDITIONS
Official Title
Outcomes of the PLHIV With Suboptimal Viral Suppression to Injectable Long-acting Antiretrovirals
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willing to sign the written informed consent form for male and female participants aged 18 and above.
- Diagnosed with HIV infection for a minimum of 12 months at enrollment.
- Receiving oral antiretroviral treatment, which may be irregular or interrupted, with the most recent viral load 200 copies/mL or higher.
- Body weight at least 35 kg.
- Willing to maintain contact with the research team throughout the study.
- Willing to receive gluteal (buttocks) drug injections.
- Willing to transition back to oral medication or follow national treatment guidelines after stopping long-acting injectables.
You will not qualify if you...
- Started or restarted oral antiretroviral therapy less than six consecutive months before screening.
- Known resistance mutations to cabotegravir or rilpivirine from previous HIV drug resistance testing.
- Unable to commit to maintaining contact with the research team throughout the study.
- Cannot receive treatment for hepatitis B during transition to long-acting injections if a hepatitis B carrier.
- Have buttock fillers.
- Women planning pregnancy, currently pregnant, or breastfeeding.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Chang Gung Memorial Hospital, Keelung
Keelung, Taiwan, 204
Actively Recruiting
2
Chang Gung Memorial Hospital, Taipei
Taipei, Taiwan, 105
Actively Recruiting
3
Taoyuan General Hospital, Ministry of Health and Welfare
Taoyuan, Taiwan, 330
Actively Recruiting
4
Chang Gung Memorial Hospital, Linkou
Taoyuan, Taiwan, 333
Actively Recruiting
Research Team
N
Nan-Yu Chen, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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