Actively Recruiting
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
Led by Mustafa Kemal University · Updated on 2026-02-02
99
Participants Needed
1
Research Sites
86 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible pulpitis, with respect to postoperative pain control and treatment success.Materials and Methods:A total of 99 mandibular premolar and molar teeth will be included in this study. The teeth will be randomly allocated into three groups (n = 33 per group): total pulpotomy, radicular pulpotomy, and root canal treatment.Root canal treatment will be performed using standardized endodontic protocols.Total pulpotomy will be carried out to the level of the canal orifices, followed by hemostasis achieved with 2.5% sodium hypochlorite (NaOCl). A 3-mm-thick layer of mineral trioxide aggregate (MTA) will be placed as the pulpotomy material.Radicular pulpotomy will be performed by removing the pulp tissue a few millimeters apical to the canal orifices. Hemostasis will be achieved using 2.5% NaOCl, and a 3-mm-thick layer of MTA will be placed as the pulpotomy agent.All treated teeth will be restored with glass ionomer cement, followed by a composite resin restoration.Postoperative pain intensity will be assessed using a visual analog scale (VAS) at the following time points: preoperatively, and at 12 hours, 24 hours, 48 hours, and 7 days postoperatively. Clinical and radiographic evaluations will be performed at 3, 6, and 12 months to assess treatment success and periapical health.
CONDITIONS
Official Title
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy patients aged 15 to 45 years with no systemic diseases
- Restorable, extremely deep carious lesions in mandibular first and second molars or premolars
- Healthy periodontal status with pocket depth of 3 mm or less
- Clinical diagnosis of symptomatic irreversible pulpitis with history of spontaneous pain and positive pulp tests
You will not qualify if you...
- Teeth with cracks or cusp fractures
- Teeth with subgingival caries
- Teeth showing periapical radiolucency
- Patients without informed consent
AI-Screening
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Trial Site Locations
Total: 1 location
1
Department of Endodontics, Faculty of Dentistry, Hatay Mustafa Kemal University
Hatay, Antakya, Turkey (Türkiye), 31000
Actively Recruiting
Research Team
E
Efkan Aksay
CONTACT
M
Merve Sarı, DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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