Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT06466382

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy

Led by Swiss GO Trial Group · Updated on 2026-05-05

60

Participants Needed

7

Research Sites

178 weeks

Total Duration

On this page

Sponsors

S

Swiss GO Trial Group

Lead Sponsor

T

Tumor Profiler Center Switzerland

Collaborating Sponsor

AI-Summary

What this Trial Is About

The long-term goal of this research project is to demonstrate whether HRD negative (HPDneg) patients benefit when additional multi-modal biological tumor information is incorporated into the molecular tumor board (mTB) treatment recommendation process.

CONDITIONS

Official Title

OV Precision: Study Examining the Benefit of a Tumor- and Patient-specific Cancer Therapy

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Newly diagnosed epithelial ovarian cancer, peritoneal, fallopian tube adenocarcinoma, or carcinosarcoma patients suspected of FIGO Stage III or IV
  • No urgent need for systemic or surgical treatment at diagnosis and for 2 weeks after
  • Planned candidate for interval debulking surgery after 2 treatment cycles
  • Able and willing to attend visits and understand trial procedures
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 to 2
  • Provided written informed consent according to legal and regulatory requirements
Not Eligible

You will not qualify if you...

  • Liver enzyme levels more than twice the normal range (ASAT > 68 U/l, ALAT > 82 U/l, GGT > 80 U/l)
  • Elevated creatinine above twice the normal range (>120 mmol/l)
  • ECOG performance status 3 or higher
  • Pregnant or breastfeeding women
  • Any other malignancy in the past 5 years affecting prognosis
  • Inability to swallow tablets
  • Currently participating in another clinical trial for the same condition
  • Any serious medical, psychiatric, psychological, family, or geographical condition that may interfere with the study or compliance

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 7 locations

1

Kantonsspital Baden AG

Baden, Canton of Aargau, Switzerland, 5404

Actively Recruiting

2

Universitätsspital Basel

Basel, Canton of Basel-City, Switzerland, 4031

Actively Recruiting

3

HOCH Health Ostschweiz Kantonsspital St.Gallen

Sankt Gallen, Canton of St. Gallen, Switzerland, 9007

Actively Recruiting

4

Thurgau AG Frauenfeld / Münsterlingen

Frauenfeld, Thurgau, Switzerland, 8500

Actively Recruiting

5

Inselspital Bern (University Hospital for Medical Oncology)

Bern, Switzerland, 3010

Actively Recruiting

6

HFR-Fribourg- Hopital Cantonal

Fribourg, Switzerland, 1708

Actively Recruiting

7

University Hospital Zurich

Zurich, Switzerland, 8091

Actively Recruiting

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Research Team

M

Maren S Vogel, PhD

CONTACT

T

Team Swiss GO Trial Group

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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