Actively Recruiting

Age: 0 - 30Years
FEMALE
NCT05309746

Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)

Led by Erin Rowell · Updated on 2024-11-18

250

Participants Needed

1

Research Sites

895 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to safely remove ovarian tissue in pediatric patients, who are at risk for infertility from their medical treatment, for freezing for future restoration of fertility and hormone function.

CONDITIONS

Official Title

Ovarian Tissue Cryopreservation in Post Pubertal (OTC-Post Pubertal)

Who Can Participate

Age: 0 - 30Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Post-pubertal individuals under 30 years of age
  • Scheduled for surgery, chemotherapy, or radiation likely to affect future fertility or hormone function
  • Treatments may include removal of ovaries, whole abdomen or pelvic irradiation ≥ 10Gy (post-pubertal) or ≥15 Gy (pre-pubertal)
  • Total body irradiation
  • Alkylating-intensive chemotherapy including cyclophosphamide, procarbazine, busulfan, or conditioning before stem cell transplant
  • Patients may have newly diagnosed or relapsed disease
  • Patients not enrolled at diagnosis but who received likely ovary-damaging therapy must provide a 4mm biopsy for research
Not Eligible

You will not qualify if you...

  • No planned oncologic therapies
  • Pregnant children
  • Children with only one ovary
  • Children at high risk for surgery complications
  • Patients unable to give consent or assent due to psychiatric or cognitive issues

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Ann &Robert H Lurie Children's Hospital

Chicago, Illinois, United States, 60611

Actively Recruiting

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Research Team

S

Sara Reyes

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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