Actively Recruiting

All Genders
NCT06355934

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis

Led by AstraZeneca · Updated on 2026-04-23

52121

Participants Needed

26

Research Sites

162 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The overall aim of this observational study is to generate real-world evidence on the pre- and post-diagnosis disease journeys, including baseline characteristics, treatment patterns and selected clinical, economic, and humanistic outcomes (for example Health Related Quality of Life (HRQoL), Neuropathy impairment score, activities of daily living (ADL) assessments) in patients with ATTR amyloidosis, and to better understand how the disease is presented.

CONDITIONS

Official Title

OverTTuRe: Characteristics, Treatment Patterns and Outcomes of Patients With ATTR Amyloidosis

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged over 18 years at the study start date
  • Reported diagnosis code for amyloidosis OR
  • Claim for ATTR-specific treatment OR
  • Positive biopsy for amyloidosis with positive immunostaining for ATTR
Not Eligible

You will not qualify if you...

  • Evidence of primary (AL) or secondary (AA) amyloidosis
  • At least one claim or procedure for stem cell transplant or two claims/procedures for chemotherapy or autoimmune disease drugs indicating AL or AA amyloidosis treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 26 locations

1

Research Site

Eden Prairie, Minnesota, United States, 55344

Completed

2

Research Site

Calgary, Alberta, Canada, T2P 4K7

Actively Recruiting

3

Research Site

Beijing, China

Completed

4

Research Site

Changsha, China

Completed

5

Research Site

Chengdu, China

Completed

6

Research Site

Guangzhou, China

Completed

7

Research Site

Wuhan, China

Completed

8

Research Site

Horsens, Denmark

Completed

9

Research Site

Berlin, Germany

Completed

10

Research Site

Tokyo, Japan

Completed

11

Research Site

Lisbon, Portugal

Actively Recruiting

12

Research Site

Porto, Portugal

Not Yet Recruiting

13

Research Site

A Coruña, Spain

Completed

14

Research Site

Barcelona, Spain

Completed

15

Research Site

Bilbao, Spain

Completed

16

Research Site

El Palmar, Spain

Completed

17

Research Site

Huelva, Spain

Completed

18

Research Site

Las Palmas de Gran Canaria, Spain

Completed

19

Research Site

Madrid, Spain

Completed

20

Research Site

Majadahonda, Spain

Completed

21

Research Site

Palma de Mallorca, Spain

Completed

22

Research Site

Salamanca, Spain

Completed

23

Research Site

Valencia, Spain

Completed

24

Research Site

Södertälje, Sweden

Completed

25

Research Site

Umeå, Sweden

Completed

26

Research Site

London, United Kingdom

Completed

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Research Team

A

AstraZeneca Clinical Study Information Center

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

6

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