Actively Recruiting
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).
Led by Ohio State University · Updated on 2024-04-26
200
Participants Needed
1
Research Sites
182 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to identify and determine the levels of oxidized lipids and lipid mediators following exposure to oxygen supplementation during mechanical ventilation by oxidative lipidomics. The investigators will include patients with mechanical ventilation and have received FiO2=\>0.5 atleast 90 minutes and collected two sequential mini bronchoalveolar lavage on them 24 hours apart. Mass Spectrometry Lipid chromatography will be conducted and clinical data will be analyzed.
CONDITIONS
Official Title
Oxidative Lipidomic Biomarkers During Mechanical Ventilation in Critically Ill Patients (OXY-BAL).
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults age 18 years or older needing mechanical ventilation in the intensive care unit expected for at least 48 hours
You will not qualify if you...
- Mechanical ventilation only needed for procedures such as bronchoscopy, esophagogastroduodenoscopy, or colonoscopy
- Chronic respiratory failure before hospital admission
- Hemoptysis or diffuse alveolar hemorrhage
- Use of medications such as N-acetyl cysteine, aspirin, or fish oil supplements
- Bronchoscopy prohibited by primary team for clinical or safety reasons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ohio State University Medical Center
Columbus, Ohio, United States, 43210
Actively Recruiting
Research Team
S
Sarah Karow
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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