Actively Recruiting

Phase 2
Phase 3
All Genders
NCT06910579

Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers

Led by British University In Egypt · Updated on 2025-09-18

30

Participants Needed

1

Research Sites

56 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Interventions of both groups: Oxygenated gel Group: 15 patients who used oxygenated gel (Blue®m, Wijhe, Netherlands) were trained by the co-investigator (A.H) through real demonstration for topical application of the gel on aphthous ulcers, which entails the application of 1-2 ml of oxygenated gel directly to the ulcer two times per day and this was repeated for 7 days. Triamcinolone acetonide Group: 15 patients were treated with Kenalog in orabase (Triamcinolone acetonide 0.1% oral paste 5g), four times (i.e., at 8 am, 12 noon, 4 pm, and 8 pm) a day for 7 days at intervention group. Patients in both groups were reexamined after treatment at different intervals (day 3, day 5, day 7, and day 10).

CONDITIONS

Official Title

Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Clinically diagnosed with chronic aphthous stomatitis with a single ulcer measuring 6 mm or less in the oral cavity
  • Provided written consent to participate
  • Systemically healthy patients
Not Eligible

You will not qualify if you...

  • History of associated systemic disease
  • Chronic aphthous stomatitis major, herpetic lesions, numerous aphthae, or smoking
  • Known hypersensitivity to study agents
  • Pregnancy or lactation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

British University in Egypt

Al Sherouk City, Cairo Governorate, Egypt, 11837

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Oxygenated Gel Therapy in the Management of Oral Aphthous Ulcers | DecenTrialz