Study Evaluating Colon Oxygen Levels in Adults With and Without Vascular Lesions of the Proximal Colon

What this Trial Is About

This research aims to evaluate oxygen levels in the colon of adults with acquired vascular abnormalities compared to healthy individuals. These vascular lesions, such as angiodysplasia, AVM, and hemangiomas, occur in the large bowel and may cause bleeding or iron deficiency anemia. The cause of these lesions is unknown, but they are more common in older adults and those with cardiac, pulmonary, or renal diseases, possibly linked to chronic low oxygen levels. Participants are divided into two groups those with vascular abnormalities in the proximal colon and those with a healthy colon. The study measures oxygen saturation at five locations in the proximal colon mucosa during a standard colonoscopy. This is a non-randomized, parallel-group study assessing oxygen levels over a 12-month period. During the study, participants undergo standard colonoscopy procedures where oxygen saturation measurements are taken. Researchers analyze quantitative oxygen levels in the colon mucosa as the primary outcome. The study includes adults aged 18 to 89 years and monitors participants up to 12 months to compare oxygenation between affected and healthy colons.

Oxygenation in Vascular Lesions of the Colon