Actively Recruiting
Oxytocin and Fetal Heart Rate Changes
Led by Unyime Ituk · Updated on 2025-06-04
730
Participants Needed
2
Research Sites
358 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The reported risk of nonreassuring fetal heart trace following neuraxial analgesia is 3-23%. This variability may be due to fluid and oxytocin management prior to and during the initiation of neuraxial analgesia. The study hypothesis is that decreasing the oxytocin infusion rate by 50 % prior to initiation of combined spinal epidural analgesia will cause a reduction in the incidence of adverse fetal heart rate changes.
CONDITIONS
Official Title
Oxytocin and Fetal Heart Rate Changes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy nulliparous or multiparous women at term (more than 37 weeks' gestation)
- Singleton pregnancy
- Request for neuraxial analgesia
- Use of oxytocin for induction or augmentation of labor per institutional protocols
You will not qualify if you...
- Use of chronic analgesic medications
- Prior systemic opioid labor analgesia
- Non-vertex fetal presentation
- Contraindication to neuraxial analgesia
- Category 3 fetal heart rate tracing before combined spinal epidural analgesia initiation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 2 locations
1
University of Iowa Hospitals and Clinics
Iowa City, Iowa, United States, 52245
Actively Recruiting
2
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Not Yet Recruiting
Research Team
U
Unyime Ituk
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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