Actively Recruiting
Oxytocin Rest to Reduce Cesarean Delivery
Led by Christiana Care Health Services · Updated on 2024-10-17
350
Participants Needed
1
Research Sites
103 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prolonged labor is usually managed with continuous oxytocin infusion. "Oxytocin rest" has been proposed as a strategy to resolve protracted labor in patients who have received continuous oxytocin without progress. This strategy involves discontinuing oxytocin then restarting infusion after a period of time, under the theory that washout of the oxytocin receptor will strengthen uterine contractions to improve labor progress. "Oxytocin rest" is performed on labor and delivery units across the United States. Yet, there is no randomized or prospective data to support the practice. The purpose of this study is to assess whether oxytocin rest of 60 minutes in patients with prolonged labor reduces risk for cesarean delivery.
CONDITIONS
Official Title
Oxytocin Rest to Reduce Cesarean Delivery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Singleton pregnancy with the baby positioned head-down
- Pregnancy of 36 weeks or more
- Prolonged latent labor defined as cervical dilation less than 6 cm after at least 8 hours since rupture of membranes while on continuous oxytocin infusion
You will not qualify if you...
- Any contraindication to continuous oxytocin at the time of randomization
- Anticipated cesarean section by the clinical team at randomization for reasons other than labor dystocia
- More than 18 hours between rupture of membranes and randomization
- Known intraamniotic infection at randomization
- Fetal death
- Any contraindication to vaginal delivery
- Maternal eclampsia
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
ChristianaCare Health System
Newark, Delaware, United States, 19718
Actively Recruiting
Research Team
T
Teresa C Logue
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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