Thiamine deficiency in tachypnoeic Cambodian infants.
Elizabeth M Keating, Phot Nget, Sreng Kea...
https://pubmed.ncbi.nlm.nih.gov/26744155Actively Recruiting
Led by University of Utah · Updated on 2026-01-16
284
Participants Needed
1
Research Sites
N/A
Total Duration
U
University of Utah
Lead Sponsor
K
Kilimanjaro Christian Medical Centre, Tanzania
Collaborating Sponsor
This research aims to develop and test a locally tailored intervention called P-KIDs CARE to improve the triage process for injured children in Tanzania. The study focuses on pediatric injury patients, family members, and healthcare providers in two health facilities in the Kilimanjaro Region. Researchers want to understand the barriers to timely care and improve assessment, stabilization, and referral processes to reduce delays in receiving definitive treatment. The P-KIDs CARE intervention includes two main parts: training healthcare providers with the World Health Organization's Basic Emergency Care Course, which uses presentations and hands-on practice, and an online decision support tool adapted for local needs. This tool incorporates models to assess mortality risk and assist with referral decisions. The intervention will be developed through workshops and refined with feedback from providers and community members before being piloted in the study facilities. Participants will include about 200 pediatric injury patients enrolled in a registry, 10 healthcare providers, and family members of patients. The study involves interviews, focus groups, surveys, and exit interviews to evaluate how feasible and acceptable the intervention is. Researchers will track outcomes like mortality, time to definitive care, patient disposition, and morbidity using tools such as the Glasgow Outcomes Scale-Extended Pediatrics. Data collection will occur over multiple years, including baseline and post-intervention periods separated by 1.5 years.
CONDITIONS
The P-KIDs CARE Health Systems Intervention in Tanzania
You may qualify if you...
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 year
Participants are enrolled to collect baseline data on pediatric injury outcomes and health system capacity before the intervention is implemented.
Data collected during routine care visits
Duration - Several months (intervention development and refinement period)
Healthcare providers participate in the P-KIDs CARE intervention development workshops and training, including the WHO Basic Emergency Care Course and use of a decision support tool.
Workshops and training sessions with healthcare providers
Duration - 1 year
Healthcare providers use the P-KIDs CARE intervention to assist with patient assessment, stabilization, and referral decisions.
Ongoing use of intervention during routine care
Duration - 1 year
Data is collected on patient outcomes, healthcare provider feedback, and intervention acceptability following implementation.
Post-surveys, exit interviews, and routine care data collection
Total: 1 location
1
Kilimanjaro Christian Medical Centre
Moshi, Tanzania
Actively Recruiting
E
Elizabeth M. Keating, MD, MSPH
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
1
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