Evaluating a Combined Intervention to Increase HIV Testing and Prevention Uptake Among Black Gay, Bisexual, and Same-Gender Loving Men Including Peer Navigation, Self-Testing, and Media Campaigns

What this Trial Is About

Researchers are evaluating a multi-component, multilevel HIV prevention program designed to overcome barriers and encourage HIV testing and PEP/PrEP uptake among Black men who have sex with men (MSM) aged 18 to 65 living in the New York City area. The study combines proven and new strategies integrated into a community-based organization's standard peer navigation care. It includes a social and print media campaign aimed at reducing HIV stigma and increasing testing and prevention demand in the community. The study uses a 2x2 factorial design to follow 480 eligible participants over 18 months. The interventions include TRUST, a one-session peer-led HIV self-testing program; DIY (Do It Yourself), a three-session program promoting empowerment, autonomy, stigma coping, and social support using "sexual self-care in-a-box" and peer training; and the standard of care (SOC) peer navigation program for PrEP access. Participants are randomized to one of four groups receiving different combinations of these interventions. The media campaign is launched midway through recruitment and delivered via social and print media to target geographic areas and Black MSM communities. Participants will be regularly assessed for HIV testing and PrEP uptake over the study period. Data will be collected through self-report, medical records, and urine tests measuring medication adherence. The study will also evaluate consistent HIV testing, PEP uptake, and adherence. Researchers will track exposure to the media campaign and analyze how combinations of interventions impact outcomes. Feedback on intervention feasibility, acceptability, and usability will be gathered using the Re-AIM framework, with an emphasis on implementation within the community-based organization.

P3 Trial: Estimating the Impact of a Multilevel, Multicomponent Intervention to Increase Uptake of HIV Testing and Biomedical HIV Prevention Among African-American/Black Gay, Bisexual, and Same-gender Loving Men