Evaluating Success and Safety of Physiologic Pacing Methods Using Implanted Cardiac Devices to Maintain Normal Heart Activation

What this Trial Is About

This research focuses on patients needing pacemaker or implantable cardioverter-defibrillator ICD implantation to avoid pacing-induced ventricular dyssynchrony. The study evaluates different pacing methods that maintain natural heart activation, such as His bundle pacing, left bundle branch area pacing, and conventional cardiac resynchronization therapy CRT. These methods aim to prevent negative effects linked to traditional right ventricular pacing, such as heart failure and atrial fibrillation, by preserving normal electrical heart function. Participants receive cardiac implantable electronic devices CIEDs implanted according to guidelines designed to maintain physiologic ventricular activation. The study observes these procedures as they occur, focusing on implantation success defined by stable lead placement and effective pacing thresholds. Researchers also track procedural details like venous access, duration, radiation exposure, and any adverse events. Data collected includes device performance and patient outcomes over time, including heart function assessments. During the study, participants undergo routine follow-up visits where device function, electrocardiograms, and echocardiograms are evaluated. Researchers monitor pacing system performance and clinical outcomes, correlating these with patient characteristics and procedural techniques. The study collects anonymized data in a secure database and expects to include around 200 patients. This observational study aims to advance understanding of the safety, effectiveness, and practical use of physiologic pacing methods.

Pacing to Maintain Physiologic Ventricular Activation