Actively Recruiting

Phase Not Applicable
Age: 0 - 18Years
All Genders
ID06886529

Early PACT Involvement in Cardiology Patients Using Machine Learning

Led by The Hospital for Sick Children · Updated on 2026-04-23

1000

Participants Needed

1

Research Sites

15 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the effectiveness of a machine-learning (ML) model in predicting serious cardiac events within three months among pediatric cardiac inpatients. The study focuses on determining whether the ML model increases palliative care team (PACT) consultations, reduces time to consultation, decreases ICU deaths, and improves documentation of care goals. The study is conducted at The Hospital for Sick Children, leveraging their strong collaboration between cardiology and palliative care. The ML model identifies high-risk cardiology patients daily. If a patient was seen by PACT in the past year, the update goes to the PACT team; otherwise, the cardiology physician in charge receives the alert to decide on consultation. The study compares patient outcomes before and after deploying the ML model, with a pre-deployment period covering 12 months starting 15 months before deployment, and a post-deployment period covering 12 months beginning 3 months after deployment. Participants are pediatric cardiology inpatients. Researchers will monitor PACT consultations within three months of admission, time to consultation, ICU death rates, and documentation of care goals. Outcomes among identified high-risk patients will be compared between the pre- and post-deployment periods to assess the ML model's impact on care processes and patient outcomes.

CONDITIONS

Brief Title

PACT Involvement in Cardiology Patients

Who Can Participate

Age: 0 - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Pediatric inpatients admitted to cardiology
Not Eligible

You will not qualify if you...

  • Expected to be discharged prior to midnight on the day of admission

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

ML-based Intervention

Duration - Up to 3 months following enrolment

Participants identified by a machine learning model as having the highest risk of serious cardiac outcomes receive earlier involvement from the palliative care team.

Participants may have palliative care consultations or visits as indicated within 3 months

Follow-up

Duration - Up to 3 months following intervention

Participants are monitored for outcomes including palliative care involvement and clinical events for up to 3 months after enrolment.

Ongoing monitoring with no required visits beyond standard care

Trial Site Locations

Total: 1 location

1

The Hospital for Sick Children

Toronto, Canada, M5G1X8

Actively Recruiting

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Research Team

L

Lillian Sung, MD, PhD

A

Agata Wolochacz, BMSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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Published Research Related To This Trial

Treatment of breakthrough and prevention of refractory chemotherapy-induced nausea and vomiting in pediatric cancer patients: Clinical practice guideline update.

Priya Patel, Paula D Robinson, Robert Phillips...

https://pubmed.ncbi.nlm.nih.gov/37178438