Post-TB lung function, quality of life, and radiographic findings in children.
G L Becker, H Kisembo, Y Sato...
https://pubmed.ncbi.nlm.nih.gov/40657266/Actively Recruiting
Led by University of Iowa · Updated on 2025-08-11
40
Participants Needed
1
Research Sites
N/A
Total Duration
This research aims to determine if a home-based pulmonary rehabilitation program is practical and acceptable for children aged 6 to 15 who have recently completed treatment for pulmonary tuberculosis. It focuses on understanding if children and their caregivers can follow the program and whether they find it feasible and acceptable. The study also explores early changes in walking distance and quality of life among participants with post-tuberculosis lung disease PTLD. The study involves a 6-week home-based rehabilitation program consisting of twice-weekly walking and wall sit exercises, guided by a physiotherapy assessment. Participants receive exercise instructions, a pedometer to track activity, and an exercise workbook. Caregivers supervise the exercises, and study staff provide weekly follow-up through phone calls or home visits. Before starting, children attend a clinic visit for baseline tests including a 6-minute walk test and a respiratory questionnaire, and they return at 6 weeks for follow-up assessments. Participants will complete physical activity exercises at home while researchers monitor adherence and acceptability over the 6-week period. Assessments include measuring walking distance, respiratory health via questionnaire scores, and body mass index changes. The study emphasizes feasibility in a low-resource setting and aims to inform future trials. Overall participation lasts about 6 weeks with regular check-ins and two clinic visits for testing.
CONDITIONS
Paediatric Post-TB Pulmonary Rehab Study
G
Greta L Becker, MD
B
Brooks Jackson, MD, MBA
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University of Iowa
Lead Sponsor
MU-JHU CARE
Collaborating Sponsor
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 6 weeks
Participants engage in a 6-week home-based pulmonary rehabilitation program that includes twice-weekly walking and wall sit exercises supervised by caregivers, guided by physiotherapy assessment. Weekly monitoring is conducted through phone calls or home visits, and participants track their activity using a pedometer and an exercise workbook.
Weekly monitoring visits by phone or home visit
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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G L Becker, H Kisembo, Y Sato...
https://pubmed.ncbi.nlm.nih.gov/40657266/G B Migliori, F M Marx, N Ambrosino...
https://pubmed.ncbi.nlm.nih.gov/34615577/University of Iowa
Lead Sponsor
MU-JHU CARE
Collaborating Sponsor