Actively Recruiting

Phase Not Applicable
Age: 6Years - 18Years
All Genders
ID05555771

Determining the Effectiveness of Counterpressure Maneuvers in Pediatric Patients Presenting With Syncope to the Emergency Department

Led by Dr. Victoria Claydon · Updated on 2026-04-23

300

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

D

Dr. Victoria Claydon

Lead Sponsor

P

Provincial Health Services Authority British Columbia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying the effectiveness of counterpressure maneuvers (CPM) to prevent fainting (syncope) in children and teenagers who visit the emergency department (ED) with fainting episodes. The study aims to better understand how syncope presents in pediatric patients and to evaluate whether CPM training can help reduce future fainting episodes. This research addresses gaps in knowledge about pediatric syncope, which is often assumed to be similar to adult syncope but may have different characteristics in children. The study has two stages. In stage I, pediatric patients aged 6 to 18 who recently experienced transient loss of consciousness will complete surveys about their fainting episodes and symptoms. In stage II, patients diagnosed with vasovagal syncope will be randomly assigned to receive either usual care (behavioral advice and avoidance measures) or usual care plus training in CPM such as leg crossing, arm tensing, and squatting. CPM training is provided via handouts and videos showing how to perform these maneuvers when feeling faint. Patients will be followed for one year, reporting monthly on any fainting or near-fainting episodes. Participants will complete surveys about their symptoms and fainting recurrences, and their medical records will be reviewed throughout the study. The main outcome is the number of patients who experience fainting again within one year. Secondary outcomes include typical symptoms before fainting, causes of syncope, and how well patients manage their symptoms with CPM or usual care. Researchers will monitor safety and compare results between the groups to understand if CPM training helps prevent fainting in pediatric patients.

CONDITIONS

Brief Title

Paediatric Syncope in the Emergency Department

Who Can Participate

Age: 6Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ages 6 to 18 years inclusive
  • Presenting to the emergency department daily between 10:00 and 22:00 with resolved transient loss of consciousness within the last week
  • Able to complete surveys in English
  • Willing and able to provide consent and assent
Not Eligible

You will not qualify if you...

  • Known history of cardiac arrhythmia diagnosis such as Wolff-Parkinson-White or long QT syndrome
  • Traumatic head injury
  • New presentation of seizure disorder or epilepsy recurrence
  • Overdose or intoxication
  • Structural heart disease
  • Hypoglycemia
  • Psychogenic vasovagal syncope without prodromal symptoms
  • Previously enrolled in this study

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 1 year

Participants confirmed to have vasovagal syncope receive either usual care with behavioural interventions and avoidance measures, or usual care alongside training in counterpressure maneuvers to help prevent recurrent syncope.

Monthly surveys during the 1-year follow-up

Trial Site Locations

Total: 1 location

1

BC Children's Hospital

Vancouver, British Columbia, Canada, V6H3N1

Actively Recruiting

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Research Team

E

Erin L Williams, BSc

S

Sonia Franciosi, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Canadian Cardiovascular Society Clinical Practice Update on the Assessment and Management of Syncope.

Primary Writing Committee, Roopinder K Sandhu, Satish R Raj...

https://pubmed.ncbi.nlm.nih.gov/32624296

Canadian Cardiovascular Society and Canadian Pediatric Cardiology Association Position Statement on the Approach to Syncope in the Pediatric Patient.

Shubhayan Sanatani, Vann Chau, Anne Fournier...

https://pubmed.ncbi.nlm.nih.gov/27838109

Effectiveness of physical counterpressure maneuvers in preventing vasovagal syncope: the Physical Counterpressure Manoeuvres Trial (PC-Trial).

Nynke van Dijk, Fabio Quartieri, Jean-Jaques Blanc...

https://pubmed.ncbi.nlm.nih.gov/17045903

Diagnostic accuracy of evaluation of suspected syncope in the emergency department: usual practice vs. ESC guidelines.

Veera K van Wijnen, Reinold O B Gans, Wouter Wieling...

https://pubmed.ncbi.nlm.nih.gov/32746777

The value of the clinical history in the differentiation of syncope due to ventricular tachycardia, atrioventricular block, and neurocardiogenic syncope.

H Calkins, Y Shyr, H Frumin...

https://pubmed.ncbi.nlm.nih.gov/7709949