Actively Recruiting
Pain Control for Undergoing Costal Cartilage Harvesting
Led by Mayo Clinic · Updated on 2025-09-12
60
Participants Needed
1
Research Sites
225 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.
CONDITIONS
Official Title
Pain Control for Undergoing Costal Cartilage Harvesting
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of functional nasal obstruction or aesthetic nasal concern requiring nasal surgery with costal cartilage harvest
- Willing and able to understand and provide written informed consent
You will not qualify if you...
- Known pregnancy
- Women who are currently nursing a child
- History of coagulopathy, such as hemophilia or Von Willebrand disease, or any congenital or acquired bleeding disorder
- Use of anticoagulation medication during the study, including aspirin, Coumadin, Plavix, or similar medications
- Inability to provide informed consent (patients under guardianship)
- Known hypersensitivity to local anesthetics
- History of cardiac disease, including impaired cardiovascular function, past myocardial infarction, congenital heart disease, or current cardiac symptoms like angina, shortness of breath, or chest pain
- History of complex pulmonary disease, including uncontrolled asthma, COPD, or interstitial lung disease
- Impaired renal function with serum creatinine greater than 1.2 mg/dL or glomerular filtration rate below 60 mL/min/BSA within the last 3 months
- History or current hepatic disease indicated by abnormal liver function tests in the last 3 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
A
Amy Tuchscherer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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