Actively Recruiting
Pain in Juvenile Arthritis
Led by Washington University School of Medicine · Updated on 2025-10-16
140
Participants Needed
1
Research Sites
519 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disease in children. The main symptoms of JIA, which are often the primary focus of treatment, include joint swelling, stiffness, and tenderness. Additional symptoms can include malaise, fatigue, and pain. However, the exact mechanisms contributing to pain are not yet fully understood. Participants will complete a 2.5-hours study session. In the study session, psychophysical assessments of thermal and pressure stimuli will be performed. In addition, demographic, social, pubertal maturation, and behavioral and psychological factors will be collected via questionnaires. A saliva sample and/or blood draw may occur for the analysis of various immune factors and sex hormones. If a joint aspiration is done as part of their standard of care, we will request a sample of the synovial fluid for analyses of immune, hormonal and/or genetic factors. Participants will have the option to participate in additional optional follow-up study visits (every 3 months, up to 1 year) and to complete monthly surveys asking about their juvenile arthritis.
CONDITIONS
Official Title
Pain in Juvenile Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 9 and 17 years
- Males and females
- English speakers
- Able to complete surveys and understand study instructions
- Diagnosed or suspected of juvenile arthritis (juvenile arthritis group)
- Healthy participants (control group)
You will not qualify if you...
- Pregnancy or breastfeeding
- For control group: diagnosed with a chronic pain condition
- For control group: diagnosed with a psychiatric condition including ADHD, anxiety, depression, etc.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Washington University School of Medicine
St Louis, Missouri, United States, 63017
Actively Recruiting
Research Team
A
Alana McMichael, MA
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here