Actively Recruiting

Age: 18Years - 50Years
All Genders
Healthy Volunteers
NCT06526572

Pain Measured by NRS and EEG in Acute Pulpitis

Led by Cleveland Dental Institute · Updated on 2024-07-31

50

Participants Needed

1

Research Sites

82 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB). The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG). By integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population. Ultimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.

CONDITIONS

Official Title

Pain Measured by NRS and EEG in Acute Pulpitis

Who Can Participate

Age: 18Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 50 years
  • Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings
  • Demonstrates resistance to inferior alveolar nerve block (IANB)
  • Willing and able to provide informed consent
  • Able to communicate effectively in the language used for study procedures
Not Eligible

You will not qualify if you...

  • Known neurological or psychiatric disorders affecting pain perception
  • Pregnant or breastfeeding at the time of the study
  • History of severe allergies or adverse reactions to local anesthetics or EEG gel
  • Significant medical conditions contraindicating dental procedures or EEG recordings
  • Taking medications that significantly affect pain perception (e.g., strong analgesics, sedatives)
  • Any contraindications for dental procedures or EEG recordings as determined by professionals
  • Inability to understand and follow study instructions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Dental Institute

Cleveland, Ohio, United States, 44128

Actively Recruiting

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Research Team

A

Ahmed I Basyoni

CONTACT

A

Abdelrahman Zaghloul

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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