Actively Recruiting
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Led by University of Florida · Updated on 2026-04-28
150
Participants Needed
1
Research Sites
257 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fibromyalgia (FM) is a chronic musculoskeletal pain disorder that afflicts up to 4% of the general population. The evaluation of pain mechanisms in FM has shown predominant central abnormalities and therefore has been designated as nociplastic pain syndrome. Rheumatoid arthritis (RA) is characterized by polyarthritis and pain from inflamed tissues, consistent with nociceptive pain. FM and RA patients may utilize overlapping pain mechanisms resulting in nociceptive and nociplastic pain.
CONDITIONS
Official Title
Pain Processing in Inflammatory and Non-Inflammatory Chronic Pain Syndromes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Ages 18 to 70 years
- Meets 1990 or 2011 American College of Rheumatology criteria for fibromyalgia
- Meets 2010 ACR-EULAR classification criteria for rheumatoid arthritis
- Healthy volunteers with no significant pain, fatigue, depression, or anxiety
You will not qualify if you...
- Diabetes
- Cancer
- Advanced liver, kidney, or cardiovascular disease
- Neuropathic pain
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Florida
Gainesville, Florida, United States, 32610
Actively Recruiting
Research Team
R
Roland Staud, M.D.
CONTACT
M
Melyssa M Godfrey, BS
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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