Actively Recruiting
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
Led by Staci Gruber, Ph.D. · Updated on 2026-03-30
25
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
S
Staci Gruber, Ph.D.
Lead Sponsor
E
Etheridge Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is a clinical trial of a high-cannabidiol (CBD) sublingual product compared to placebo for 9 weeks in patients with chronic pain conditions. The study will assess the impact of CBD on chronic pain symptoms, conventional medication use, clinical state, quality of life, cognition, and biomarkers.
CONDITIONS
Official Title
PAIN: A Project Assessing the Impact of a Novel Cannabinoid Product
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subject has provided informed consent
- Subject is 21 or older
- Subject is fluent in English
- Subject endorses a musculoskeletal chronic pain condition including, but not limited to, chronic pain due to injury, arthritis (including osteoarthritis and rheumatoid arthritis), bursitis, etc.
You will not qualify if you...
- Non-fluent English speakers
- Estimated IQ less than 75
- History of head injury or loss of consciousness greater than 5 minutes
- Current regular use of CBD products
- Female subjects with positive urine pregnancy test, trying to become pregnant, or breastfeeding
- Presence of serious or unstable medical illnesses, including liver, kidney, cardiovascular, or neurological disorders
- Primary neuropathic pain or cancer-related pain (neuropathic pain secondary to musculoskeletal pain allowed)
- Disclosure of a genetic polymorphism affecting CYP2C9 function
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
McLean Hospital
Belmont, Massachusetts, United States, 02478
Actively Recruiting
Research Team
S
Staci Gruber, Ph.D.
CONTACT
R
Rosie Smith, M.S.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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