Actively Recruiting
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Led by Stanford University · Updated on 2025-08-06
121
Participants Needed
2
Research Sites
291 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In the US, pain management after surgery for surgical treatment of osteoarthritis at the base of the thumb typically consists of prescription opioids during the early recovery phase. Given the highly addictive nature of prescription opioids, guidelines are being evaluated by hand surgeons to reduce opioid use while still maintaining pain control after surgery. A promising approach is to use non-narcotic medication as the first line of treatment. The purpose of this study is to demonstrate the efficacy of a combination of non-steroidal anti-inflammatory drugs (NSAIDs), ibuprofen and acetaminophen, in comparison to a morphine analogue substance (oxycodone) for pain management in the first 30 days after surgery.
CONDITIONS
Official Title
Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Undergoing trapeziectomy for thumb osteoarthritis
- English proficient
You will not qualify if you...
- Pregnancy
- Current use of opioids
- Concurrent surgeries (e.g., trapeziectomy combined with carpal tunnel release)
- Inability to complete study forms due to education, cognitive ability, mental status, or medical status
- Allergy or intolerance to ibuprofen, acetaminophen, and/or oxycodone
- Liver or kidney dysfunction or abnormal liver enzymes restricting use of acetaminophen or ibuprofen
- History of chronic heart failure, upper gastrointestinal bleeding, or coagulopathy
- History of complex regional pain syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Stanford Health Care
Redwood City, California, United States, 94063
Actively Recruiting
2
University of Utah Health Care
Salt Lake City, Utah, United States, 84112-
Actively Recruiting
Research Team
D
Deborah Kenney, MS OTR
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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