Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
MALE
Healthy Volunteers
NCT06457230

Paired-pulse rTMS Treatment for Methamphetamine Use Disorder Based on the mPFC-Cerebellum

Led by Shanghai Mental Health Center · Updated on 2025-12-18

70

Participants Needed

1

Research Sites

83 weeks

Total Duration

On this page

Sponsors

S

Shanghai Mental Health Center

Lead Sponsor

H

Hanyang Drug Rehabilitation Center

Collaborating Sponsor

AI-Summary

What this Trial Is About

To investigate the mechanism and efficacy of a novel repetitive transcranial magnetic stimulation (rTMS) intervention model with paired medial prefrontal cortex (mPFC) -cerebellar pulses on methamphetamine use in patients and to develop a novel physiotherapeutic intervention to optimise the treatment and management of addicted patients.

CONDITIONS

Official Title

Paired-pulse rTMS Treatment for Methamphetamine Use Disorder Based on the mPFC-Cerebellum

Who Can Participate

Age: 18Years - 60Years
MALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Primary substance of abuse is methamphetamine.
  • Meets DSM-5 criteria for severe methamphetamine use disorder with 6 or more symptoms in the past year.
  • Age between 18 and 60 years.
  • Education level of primary school or above with ability to understand questionnaires and tasks.
  • Normal vision and hearing; right-handed.
  • No previous participation in any TMS-related intervention therapy.
Not Eligible

You will not qualify if you...

  • Presence of any metallic implants or implanted medical devices such as pacemakers or neurostimulators.
  • Chronic or severe physical illnesses, including heart conditions, uncontrolled hypertension, or physical disabilities.
  • Comorbid psychiatric disorders such as schizophrenia, depressive disorders, or anxiety disorders.

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Min Zhao, PhD

Shanghai, Shanghai Municipality, China, 200000

Actively Recruiting

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Research Team

M

Min Zhao, PhD

CONTACT

6

64387250 Zhao, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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