Actively Recruiting
Paired tVNS With ERP in OCD
Led by University of Florida · Updated on 2025-10-27
56
Participants Needed
1
Research Sites
218 weeks
Total Duration
On this page
Sponsors
U
University of Florida
Lead Sponsor
I
International OCD Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
In the proposed investigation, the investigator will develop pilot data for the use of tVNS (transcutaneous vagal nerve stimulation) to enhance efficacy of exposure and response prevention therapy (ERP) to improve treatment success in patients with OCD. This data will include tolerability information from therapists and patients with OCD, effect sizes on real world clinical outcomes for the combinatory treatment, and mechanistic data on brain changes associated with treatment.
CONDITIONS
Official Title
Paired tVNS With ERP in OCD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults between the ages of 18 and 55
- Meet DSM-5 criteria for OCD based on a structured clinical interview
- Have a Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score of 15 or higher
- Willing and able to provide informed consent
You will not qualify if you...
- Major neurological conditions, autism spectrum disorder, psychosis, major uncorrected sensory deficits, or severe medical diseases affecting the nervous system
- Active eating disorder requiring treatment (remission allowed)
- Current illicit or prescription drug abuse
- Medication changes within 6 weeks prior to study entry
- Prior ERP treatment within the last 12 months
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Florida
Gainesville, Florida, United States, 32610
Actively Recruiting
Research Team
L
Laura Jones, M.S.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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