Actively Recruiting
PAlliative RAdioTherapy to Lung Cancer A Randomized Multicentre Phase III Study
Led by University of Aarhus · Updated on 2024-05-08
1184
Participants Needed
1
Research Sites
349 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to examine if a shorter palliative radiotherapy fractionation scheme of 20 Gy / 4 F can reduce the early oesophageal toxicity compared to 30 Gy / 10 F in patients with lung cancer in performance status (PS) 0-2. Secondary aims are to examine the effect on lung cancer symptoms, quality of life (QoL) and survival. Furthermore, the investigators aim at standardizing the quality of palliative thoracic radiotherapy in all Danish centres at the highest technical level.
CONDITIONS
Official Title
PAlliative RAdioTherapy to Lung Cancer A Randomized Multicentre Phase III Study
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologically or cytologically confirmed non-small cell or small cell lung cancer.
- Stage III or IV lung cancer not eligible for curative treatment.
- Age 18 years or older.
- Performance status of 0 to 2.
- Signed informed consent.
- Fertile women must have a negative pregnancy test and use effective contraception during the study and for one month after.
- Fertile men and women must use effective contraception during the study and for one month after.
You will not qualify if you...
- Previous radiotherapy to the thorax that prevents safe delivery of 30 Gy in 10 fractions due to organ dose limits.
- Inability to understand or communicate in the language used for study information.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Aarhus University Hospital
Aarhus, Denmark
Actively Recruiting
Research Team
M
Marianne Marquard Knap, PhD, MD
CONTACT
L
Lone Hoffmann, PhD,
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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