Actively Recruiting

Age: 21Years - 99Years
All Genders
NCT06418412

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

Led by National Cancer Centre, Singapore · Updated on 2025-06-12

600

Participants Needed

3

Research Sites

145 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

There are limited in depth studies on the epidemiology and clinical management of EGFR exon 20 insertion mutated NSCLC in Asia. In addition, there is preliminary data suggesting the exact location of the insertion and variant may influence the response and efficacy to novel EGFR targeted therapies. This study aims to fill this knowledge gap, by comprehensively characterising the epidemiology and clinical outcomes of Asian advanced EGFR exon 20 insertion mutated NSCLC patients.

CONDITIONS

Official Title

A Pan-Asian Clinical Database of EGFR Exon 20 Insertion Mutated NSCLC

Who Can Participate

Age: 21Years - 99Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically confirmed advanced NSCLC
  • Positive test result for EGFR exon 20 insertion mutation using any locally approved test
  • Diagnosis date between January 1, 2013 and December 31, 2024
  • Male or female adults, age as defined by local regulations
Not Eligible

You will not qualify if you...

  • Patients without an EGFR exon 20 insertion mutation

AI-Screening

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Trial Site Locations

Total: 3 locations

1

National Cancer Centre, Singapore

Singapore, Singapore, 168583

Actively Recruiting

2

Seoul National University Hospital

Seoul, South Korea

Actively Recruiting

3

National Taiwan University Hospital

Taipei, Taiwan

Actively Recruiting

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Research Team

C

Cherlyn Shepherdson

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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