Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06330441

Pancreatic Cancer Screening in a Population at High Risk

Led by Masaryk Memorial Cancer Institute · Updated on 2026-04-21

700

Participants Needed

1

Research Sites

312 weeks

Total Duration

On this page

Sponsors

M

Masaryk Memorial Cancer Institute

Lead Sponsor

M

Masaryk University

Collaborating Sponsor

AI-Summary

What this Trial Is About

Pancreatic cancer is one of the diseases with the worst prognosis, which is mainly due to the initial asymptomatic prognosis. Unfortunately, the incidence of this disease in the Czech Republic is still increasing. In a certain proportion of patients, it is possible to predict the disease, e.g. due to family burdens. Regular follow-up of such individuals is the subject of the SCREPAN study: "Pancreatic Cancer Screening in High-Risk Persons".

CONDITIONS

Official Title

Pancreatic Cancer Screening in a Population at High Risk

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Willing to participate in the study
  • Age 18 years or older
  • For Arm A: chronic pancreatic disease related to cystic fibrosis or chronic pancreatitis and age 50 years or older
  • For Arm B1: confirmed Peutz-Jeghers syndrome or familial melanoma syndrome or hereditary pancreatitis with specific age criteria or timing after first attack
  • For Arm B2: confirmed diagnosis of hereditary syndromes (Lynch, HBOC, familial adenomatous polyposis, Li-Fraumeni) with at least one relative diagnosed with pancreatic ductal adenocarcinoma and age 50 or older or 10 years before youngest relative's diagnosis
  • For Arm C: positive family history of pancreatic ductal adenocarcinoma without hereditary syndrome, age 50 or older or 10 years before youngest affected relative
Not Eligible

You will not qualify if you...

  • Unable to undergo radical curative surgery for pancreatic tumor
  • Unable to undergo scheduled imaging examinations
  • Having incurable malignant cancer

AI-Screening

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Trial Site Locations

Total: 1 location

1

Masaryk Memorial Cancer Institute

Brno, Czechia, 65653

Actively Recruiting

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Research Team

M

Martina Lojova, Ph.D.

CONTACT

D

Dita Kozakova, Ing.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

SCREENING

Number of Arms

4

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