Actively Recruiting
Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors
Led by Institut Paoli-Calmettes · Updated on 2025-05-25
82
Participants Needed
1
Research Sites
522 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Pancreatic radiofrequency ablation (RFA) could therefore be an alternative to the monitoring of pancreatic neuroendocrine tumors (PNETs) and more particularly nonfunctioning PNETs (NF-PNETs), which is costly and anxiety-inducing for patients. To date, only a few small studies have evaluated this treatment and the results are encouraging. It appears necessary to consider a large-scale study to ensure the efficacy and low morbidity of pancreatic RFA applied to PNETs.
CONDITIONS
Official Title
Pancreatic Radiofrequency Under High Echo-endoscopy in the Management of Pancreatic Neuroendocrine Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pancreatic mass less than 2cm on MRI or CT scan if MRI is contraindicated
- Diagnosis of neuroendocrine tumor on biopsy under high echo-endoscopy with Ki67 less than 3%
- Non-secretory lesion
- Homogeneous contrast uptake on high echo-endoscopy
- No FDG binding on PET scan to the pancreatic mass
- Lesion less than 20mm on conventional imaging after 6 months monitoring
- Age between 18 and 80 years inclusive
- Good general health, World Health Organization status 0-1
- Signed consent to participate
- Affiliated to a healthcare insurance system or beneficiary of such
You will not qualify if you...
- Pregnant, likely to become pregnant without effective contraception, or breastfeeding
- Emergency situation, deprived of liberty, or under tutorship
- Life expectancy less than 1 year
- Severe blood clotting disorders
- Dilation of pancreatic and/or biliary ducts
- Lesion adjacent to pancreatic or bile ducts
- Lymph node extension or metastatic disease
- Being treated for another progressing malignant lesion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institut Paoli Calmettes
Marseille, France, 13009
Actively Recruiting
Research Team
J
Jihane PAKRADOUNI
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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