Actively Recruiting

Phase 1
Phase 2
Age: 6Months - 25Years
All Genders
NCT04085887

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Led by Stanford University · Updated on 2026-03-20

12

Participants Needed

1

Research Sites

139 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of the study is to assess safety of panitumumab-IRDye800 in pediatric patients undergoing brain surgery to remove suspected tumors.

CONDITIONS

Official Title

Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures

Who Can Participate

Age: 6Months - 25Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suspected brain tumors requiring surgical removal as standard care
  • Eligible for tumor resection as determined by the surgeon
  • Planned standard of care surgery
  • Age between 6 months and 25 years
  • Life expectancy greater than 12 weeks
Not Eligible

You will not qualify if you...

  • Received investigational drug within 30 days before Panitumumab-IRDye800 dose
  • History of heart attack, stroke, uncontrolled heart failure, significant liver disease, or unstable angina within 6 months
  • History of infusion reactions to monoclonal antibody therapies
  • Pregnant or breastfeeding
  • QTc prolongation on ECG beyond specified limits for age and sex
  • Low magnesium, potassium, or calcium lab values below normal limits
  • Serum creatinine above 1.5 times the upper reference range
  • Lab values preventing surgical resection as judged by the surgeon
  • Use of certain antiarrhythmic drugs (Class IA or III)
  • History or evidence of interstitial pneumonitis or pulmonary fibrosis
  • Not suitable candidates for optimal tumor resection due to tumor location or other factors

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford Cancer Center

Stanford, California, United States, 94304

Actively Recruiting

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Research Team

N

Nancy Sweeters

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

DIAGNOSTIC

Number of Arms

4

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Panitumumab-IRDye800 to Detect Pediatric Neoplasms During Neurosurgical Procedures | DecenTrialz