Actively Recruiting

Phase Not Applicable
Age: 50Years +
All Genders
ID06444841

Smartphone-Based Solutions for Prospective Memory in Mild Cognitive Impairment and Dementia

Led by Baylor University · Updated on 2024-07-09

200

Participants Needed

3

Research Sites

N/A

Total Duration

On this page

Sponsors

B

Baylor University

Lead Sponsor

U

University of Texas at Austin

Collaborating Sponsor

AI-Summary

What this Trial Is About

Alzheimer's disease, mild cognitive impairment, and related dementias cause significant declines in daily functioning and independence. This research aims to evaluate the effectiveness of smartphone-based memory aids compared to traditional paper-based memory systems in improving prospective memory, which is the ability to remember future intentions like taking medications. The study will focus on diverse participants, including those from digitally-disadvantaged backgrounds, to assess the durability and generalizability of these memory supports. Participants will be randomly assigned to use either a smartphone app called Google Calendar, which provides digital reminders for personal and study-related tasks, or a paper-based Memory Support System, a portable calendar and note-taking notebook. Both groups will receive booster training sessions over a 4-week intervention period to help build confidence in using their assigned memory aid. Follow-up assessments will occur at 3 and 6 months to measure lasting benefits. Throughout the study, participants will complete various memory and cognitive tests, including patient-selected and assigned prospective memory assessments. Study partners will also be enrolled to provide additional insights on caregiving burden and quality of life. Researchers will collect data on smartphone usage, cognitive function, mood, sleep, and life satisfaction. The total participation time extends to 6 months to evaluate outcomes and potential improvements in both participants and their caregivers.

CONDITIONS

Brief Title

Paper-Based and Smartphone-Based Memory Supports

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Demonstrate capacity to consent via structured interview or have surrogate consent available
  • Diagnosis consistent with mild cognitive impairment or mild dementia using clinical records or clinical interview
  • Montreal Cognitive Assessment (MoCA) scores between 17-25 (12-18 for telephone version) with demographic adjustments
  • Functional status indicating independence in basic self-care (Global Deterioration Scale stage 3 or 4)
  • Adequate sensory and motor abilities to use a smartphone with accommodation
  • Availability of a co-participant who sees the participant at least once a month
  • Co-participant must be over 18, consent to participation, and see the participant monthly
Not Eligible

You will not qualify if you...

  • History of serious mental illness such as schizophrenia or bipolar disorder as primary cause of cognitive decline
  • Moderate or severe dementia indicated by clinical documentation, MoCA score, or Global Deterioration Scale score of 5 or higher
  • Significant language difficulties interfering with screening
  • Uncorrected hearing loss, vision loss, or motor dysfunction interfering with training
  • No study partner available
  • Individuals not conversational in English are excluded
  • Co-participant sees participant less than once per month or is not conversational in English

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 1 month

Participants use either a smartphone-based app or a paper-based memory support system to help with prospective memory tasks. This phase includes training and booster sessions throughout the intervention period.

Weekly visits for up to 1 month

Outpatient Treatment

Duration - 6 months

Participants continue to use their assigned memory support system (digital or paper-based) to manage prospective memory tasks and daily activities.

Monthly visits for up to 6 months

Trial Site Locations

Total: 3 locations

1

UT Health Austin Comprehensive Memory Center

Austin, Texas, United States, 78712

Actively Recruiting

2

Baylor Scott & White Healthcare

Temple, Texas, United States, 76508

Not Yet Recruiting

3

Baylor University

Waco, Texas, United States, 76798

Actively Recruiting

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Research Team

M

Michael Scullin, PhD

J

Jared Benge, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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