Actively Recruiting
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
Led by University of North Carolina, Chapel Hill · Updated on 2025-10-24
56
Participants Needed
1
Research Sites
58 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The goal of the study to see if giving a numbing medicine around the cervix (called a paracervical block) during vaginal hysterectomy with prolapse repair helps people feel less pain and need fewer strong pain medicines afterward. The main question it aims to answer is: • Does receiving a paracervical block at the time of vaginal hysterectomy with prolapse repair reduce postoperative opioid use? Researchers will compare opioid use in participants who receive the an injected numbing medicine (bupivacaine with lidocaine) to those that receive a saltwater liquid placebo. Participants will: * Receive either an injection of the numbing medicine (bupivacaine with lidocaine) or saltwater liquid placebo after they are asleep but before any other parts of the surgery are done * Record and report pain medications used for 7 days after surgery * Report pain scores before discharge from the post anesthesia recovery area on day of surgery as well as 1 and 7 days after surgery * Complete a surgical recovery questionnaire during 6 week postoperative visit * Complete a one page multiple-choice test on pelvic organ prolapse
CONDITIONS
Official Title
Paracervical Injection and Opioid Use After Vaginal Hysterectomy for Prolapse
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals undergoing vaginal hysterectomy with concomitant prolapse repair procedure
You will not qualify if you...
- Non-English speaking
- Weight less than 50 kg
- Allergy to bupivacaine
- Pregnant
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
University of North Carolina Urogynecology and Reconstructive Pelvic Surgery at REX
Raleigh, North Carolina, United States, 27607
Actively Recruiting
Research Team
B
Bertie Geng, MD
CONTACT
M
Marcella Willis-Gray, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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