Parasternal intercostal muscle thickening as a predictor of non-invasive ventilation failure in patients with COVID-19.
Mina Adlof Helmy, Ahmed Hasanin, Lydia Magdy Milad...
https://pubmed.ncbi.nlm.nih.gov/35487407Actively Recruiting
Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07143695
Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion to Minimize Re-intubation Rate: a Randomized Controlled Trial
Led by Cairo University · Updated on 2025-09-08
200
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Increased days of MV are not without hazards, including barotraumas and ventilator-associated pneumonia. Similarly, premature separation of MV is associated with increased mortality secondary to adverse cardiorespiratory events. Therefore, the time of weaning should be wisely evaluated. There is growing evidence concerning respiratory muscles dysfunction that contributes to difficulty or prolonged liberation from MV.
CONDITIONS
Brief Title
Parasternal Intercostal Muscle Thickening as an Additive Weaning Criterion
Who Can Participate
Age: 18Years - 65Years
All Genders
Eligibility Criteria
You may qualify if you...
- critically ill patient mechanically ventilated for 24 hours or more first spontaneous breathing trial
You will not qualify if you...
- patient refusal difficult ultrasound views tracheostomized patient neuromuscular disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Giza Governorate, Egypt, 6890
Actively Recruiting
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Research Team
C
Cairo university
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Published Research Related To This Trial
Parasternal intercostal thickening at hospital admission: a promising indicator for mechanical ventilation risk in subjects with severe COVID-19.
Mina A Helmy, Lydia M Milad, Ahmed M Hasanin...
https://pubmed.ncbi.nlm.nih.gov/36961635Ability of parasternal intercostal muscle thickening fraction to predict reintubation in surgical patients with sepsis.
Mina Adolf Helmy, Ahmed Hasanin, Lydia Magdy Milad...
https://pubmed.ncbi.nlm.nih.gov/39174907