Actively Recruiting
Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
Led by University Hospital, Bordeaux · Updated on 2025-05-02
20
Participants Needed
1
Research Sites
102 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Bordeaux
Lead Sponsor
U
Université de Bordeaux, IMN, UMR CNRS 5293
Collaborating Sponsor
AI-Summary
What this Trial Is About
Expression of hypokinetic and hyperkinetic motor symptoms in Parkinson's disease (PD) is associated with pathological synchronous oscillations of neuronal activity (local field potential/LFP) in the cortico-subcortical network with a wide frequency range. In the present project, we propose to study cortico-subcortical oscillations and their synchronization in patients operated for PD (subthalamic deep brain stimulation (STN-DBS)) during distinct pharmacological and stimulation conditions (hypokinetic and hyperkinetic), using a simple motor task.
CONDITIONS
Official Title
Parkinsonism-Related Oscillations in the Cortico-Basal Ganglia-Thalamic Network During Movement: Beyond the Frequency Range
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or Female
- 18 to 75 years-old
- With idiopathic Parkinson's disease
- Having a STN-DBS with a PERCEPT12 for less than a year or being candidate for STN-DBS with the PERCEPT12 device (first-implantation)
- Able to perform the simple motor task
- Patients covered by a health insurance scheme
- Giving free, informed, written consent signed by the participant and the investigator.
You will not qualify if you...
- Be incapable of giving consent personally.
- Be subject to a legal protection measure (curatorship, guardianship) or be placed under judicial protection.
- Being pregnant or breastfeeding
- Present a serious and/or decompensated somatic or psychiatric illness.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Bordeaux University Hospital
Bordeaux, France
Actively Recruiting
Research Team
G
GUEHL Dominique, Pr
CONTACT
C
Claire BRANDET
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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