Study of Passive Calf Muscle Stretching to Improve Muscle and Walking in Peripheral Artery Disease Patients Aged 40 to 85

What this Trial Is About

Researchers are evaluating the effects of passive calf muscle stretching in people diagnosed with peripheral artery disease PAD. The study aims to determine if daily calf muscle stretching at home can improve calf muscle and blood vessel health, as well as walking ability. The trial is led by Penn State University and involves participants aged 40 to 85 years. Participants will use a modified plantar fasciitis ankle splint to passively stretch their calf muscles on both feet for 30 minutes a day, five days a week, over a period of four weeks. Another group will not use the stretching device and will continue their usual daily activities for four weeks. The study compares the effects of stretching versus no stretching. Throughout the study, researchers will measure walking performance using a 6-minute walk test, assess muscle and tendon size, and evaluate blood vessel function. Joint and foot movements, as well as calf muscle oxygen levels, will be monitored during walking tests. Participants will be involved for at least eight weeks, including four weeks of stretching or no stretching and assessments before and after these periods.

Passive Calf Stretching Therapy in Peripheral Artery Disease