Actively Recruiting
Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness
Led by CentraCare · Updated on 2024-08-22
64
Participants Needed
1
Research Sites
100 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In the critically ill population, fluid administration in an unstable patient is perhaps the most common intervention that is performed. Uncorrected hypovolemia with inappropriate vasopressors lead to organ hypoperfusion where as overzealous fluid administration especially in ARDS (Adult respiratory distress syndrome) can increase mortality. It has been estimated that only 50% of hemodynamically unstable critically ill patients are volume responsive, hence dynamic assessment of preload responsiveness has been proposed to better identify those individuals who would benefit from fluid bolus.
CONDITIONS
Official Title
Passive Leg Raise and Mini-fluid Challenge Effect on Various Cardiac Output Surrogates for Fluid Responsiveness
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 30 and 90 years
- Diagnosis of vasodilatory shock with no other obvious cause of hypotension
- Diagnosis of ARDS with PF ratio less than 150 and PEEP greater than 8
- Patients who are paralyzed or deeply sedated and on mechanical ventilation
You will not qualify if you...
- Patients with arrhythmias including atrial fibrillation
- Patients with chest tube, intra-abdominal hypertension, or risk factors for these
- Patients with structural heart disease including pulmonary hypertension (RVSP > 45) and heart failure
- Patients on extracorporeal support such as ECMO, CRRT, or mechanical circulatory support
- Patients with COPD with a premorbid FEV1 less than 1.5 L
- Patients with severe atherosclerotic vascular disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
St Cloud Hospital
Saint Cloud, Minnesota, United States, 56303
Actively Recruiting
Research Team
R
Ramakanth Pata
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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