Actively Recruiting

Phase Not Applicable
Age: 3Years - 12Years
All Genders
NCT05440448

Patch-free Occlusion Therapy

Led by Retina Foundation of the Southwest · Updated on 2026-01-07

68

Participants Needed

1

Research Sites

218 weeks

Total Duration

On this page

Sponsors

R

Retina Foundation of the Southwest

Lead Sponsor

N

National Eye Institute (NEI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of the study is to determine whether a patch-free occlusion therapy leads to better visual outcomes in young children with amblyopia than standard-of-care occlusion therapy with an adhesive patch and whether this is associated with better adherence to the treatment.

CONDITIONS

Official Title

Patch-free Occlusion Therapy

Who Can Participate

Age: 3Years - 12Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 3-12 years
  • male and female
  • strabismic, anisometropic, or combined mechanism amblyopia (visual acuity: 0.3-0.8 logMAR)
  • interocular visual acuity difference ≥0.3 logMAR
  • wearing glasses (if needed) for a minimum of 8 weeks with no change in visual acuity at 2 visits ≥4 weeks apart
  • child's ophthalmologist and family willing to forgo standard patching treatment during the study
Not Eligible

You will not qualify if you...

  • Prematurity ≥8 wk
  • coexisting ocular or systemic disease
  • developmental delay
  • myopia > -3.00D

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Retina Foundation

Dallas, Texas, United States, 75231

Actively Recruiting

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Research Team

E

Eileen E Birch, PhD

CONTACT

R

Reed M Jost, MS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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