Actively Recruiting
Pathogen-Reduced Platelet Concentrates: Experience in Routine Practice in Germany
Led by Deutsches Rotes Kreuz DRK-Blutspendedienst Baden-Wurttemberg-Hessen · Updated on 2026-01-21
850
Participants Needed
1
Research Sites
75 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
* Overall objective: to accumulate further experience with the use of pathogen-reduced platelet concentrates throughout the entire process chain from manufacture to clinical use of pathogen-reduced platelet concentrates and their efficacy and safety under real-world conditions. The study aims to better understand the impact of pathogen inactivation on the various steps of the overall supply chain in routine practice, whereby safety, measured in terms of the frequency of serious transfusion reactions and the type, imputability, and outcome of the reactions, is the primary endpoint. * Study product: Pathogen-reduced platelet concentrates. * Methodology: multi-center, open-label, prospective, non-interventional safety study.
CONDITIONS
Official Title
Pathogen-Reduced Platelet Concentrates: Experience in Routine Practice in Germany
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 18 years or older
- Patients who need at least one platelet transfusion with pathogen-reduced platelet concentrates for bleeding risk caused by severe thrombocytopenia due to impaired platelet production
- Transfusion indication based on current German Medical Association guidelines
You will not qualify if you...
- Known hypersensitivity to amotosalen HCl or psoralens
- Known allergies to human plasma proteins
- Diagnosis of immune thrombocytopenia
- Presence of thrombotic microangiopathy, including thrombotic thrombocytopenic purpura or hemolytic uremic syndrome
- History of post-transfusion purpura
- Diagnosis of heparin-induced thrombocytopenia
- Congenital platelet function disorders such as Glanzmann's thrombasthenia or Bernard-Soulier syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institut für Klinische Transfusionsmedizin (IKT) und DRK Blutspendedienst Baden-Württemberg-Hessen/ Transfusionsambulanz MVZ DRK-Blutspendedienst Ulm gGmbH
Ulm, Baden-Wurttemberg, Germany, 89081
Actively Recruiting
Research Team
S
Simone Hoffmann, Dr. rer. nat.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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