Actively Recruiting
Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
Led by Yale University · Updated on 2025-01-27
260
Participants Needed
1
Research Sites
239 weeks
Total Duration
On this page
Sponsors
Y
Yale University
Lead Sponsor
N
National Institute on Minority Health and Health Disparities (NIMHD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The main aim of the study is to discover the mechanisms underlying the pathophysiology of NAFLD in obese youth.
CONDITIONS
Official Title
Pathogenesis of Pediatric Nonalcoholic Fatty Liver Disease (NAFLD)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Good general health, taking no medication on a chronic basis
- Age 12 to 18 years, in puberty (Tanner stage II-V)
- BMI greater than 85th percentile for obese cohort
You will not qualify if you...
- Baseline creatinine greater than 1.0 mg
- Pregnancy
- Presence of endocrinopathies such as Cushing syndrome
- Cardiac, pulmonary, or other significant chronic illness
- Adolescents with psychiatric disorders or substance abuse
- Monogenic obesity syndromes
- Use of drugs affecting intrahepatic fat content (e.g., liraglutide, fish oil)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Yale New Haven Hospital
New Haven, Connecticut, United States, 06510
Actively Recruiting
Research Team
E
Ermena REFUGJATI
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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