Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT04280510

Pathogenic Study of Adult Immune Enteropathies

Led by Institut National de la Santé Et de la Recherche Médicale, France · Updated on 2025-09-18

200

Participants Needed

4

Research Sites

678 weeks

Total Duration

On this page

Sponsors

I

Institut National de la Santé Et de la Recherche Médicale, France

Lead Sponsor

I

Imagine Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study focuses the mechanisms underlying the loss of intestinal homeostasis in celiac disease, refractory celiac disease and other immune diseases such as monogenic enteropathy, inflammatory bowel diseases or drug induced intestinal diseases. Mechanisms of transformation of lymphocytes leading to onset of lymphomatous complications of immune enteropathies will be investigated. Mechanisms of loss of hepatic lymphocytic homeostasis will also be assessed in liver associated diseases.

CONDITIONS

Official Title

Pathogenic Study of Adult Immune Enteropathies

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or over
  • Affiliated to social insurance
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Pregnancy
  • Under guardianship
  • Not able to sign informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

Hôpital Henri Mondor

Créteil, France, 94010

Not Yet Recruiting

2

Hôpital Bicêtre

Le Kremlin-Bicêtre, France, 94270

Not Yet Recruiting

3

Hôpital Saint Louis

Paris, France, 75010

Not Yet Recruiting

4

Hôpital Cochin

Paris, France, 75014

Actively Recruiting

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Research Team

G

Georgia MALAMUT, MD, PhD

CONTACT

A

Anaïs LEVESCOT, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

7

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Pathogenic Study of Adult Immune Enteropathies | DecenTrialz