Actively Recruiting

Age: 18Years +
All Genders
NCT05122962

Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases

Led by Mayo Clinic · Updated on 2026-02-05

300

Participants Needed

1

Research Sites

256 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study is being done to determine the mechanism(s) contributing to the onset of symptoms (i.e. shortness of breath and/or palpitations) as well as changes in heart structure in patients with congenital heart disease (CHD)

CONDITIONS

Official Title

Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Moderate (or greater) pulmonary regurgitation based on quantitative Doppler echocardiography
  • Repaired Tetralogy of Fallot
  • Diagnosis of congenital heart disease including but not limited to Ebstein's anomaly, coarctation of the aorta, Fontan palliation, transposition of the great arteries, or congenitally corrected transposition of the great arteries
Not Eligible

You will not qualify if you...

  • Pregnant women
  • Unable to undergo cardiac MRI (CMRI)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

H

Halley Davison

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases | DecenTrialz