Actively Recruiting
Pathophysiology of Inborn Immunodeficiencies
Led by University of Zurich · Updated on 2026-05-06
300
Participants Needed
1
Research Sites
943 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The pathophysiology of primary immunodeficiencies (PID), which encompass a broad range of different diseases with susceptibility to infection and/or a deregulated inflammatory response, is poorly understood. Available treatments are often not specific for a distinct target and might be associated with side effects. To elucidate pathophysiology of different PIDs, stool, urine, blood, tissue biopsies and/or bone marrow will be collected and analysed for anti-microbial activity and inflammatory response. In a second step, targeted treatment for different PIDs might be developed preclinically and ex vivo according to underlying pathophysiology.
CONDITIONS
Official Title
Pathophysiology of Inborn Immunodeficiencies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Clinical diagnosis of an inborn error of immunity (primary immunodeficiency, PID)
- Clinically healthy (non-age matched) volunteer
You will not qualify if you...
- Exclusion of an inborn error of immunity
- Secondary immunodeficiency
- Refusal to enter the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Children's Hospital Zurich
Zurich, Switzerland, 8032
Actively Recruiting
Research Team
J
Janine Reichenbach, Prof. Dr.
CONTACT
U
Ulrich Siler, PD Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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