Actively Recruiting
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Led by University of Texas Southwestern Medical Center · Updated on 2026-05-06
75
Participants Needed
1
Research Sites
214 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will probe if the biological changes in amnestic mild cognitive impairment (aMCI) are related to a history of mild traumatic brain injury (mTBI) using high definition transcranial direct current stimulation (HD-tDCS) and blood-derived biomarker tools. Participants who Do as well as those who Do Not have a history of mTBI will be enrolled in the study.
CONDITIONS
Official Title
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Active diagnosis of amnestic mild cognitive impairment
- History of mild traumatic brain injury for the mTBI+ group; no mTBI history for control group
- Female and male subjects
- All races and ethnicities
- Age 55 years and older
- Fluent in English
You will not qualify if you...
- Mild traumatic brain injury within the past year
- Lifetime history of moderate or severe brain injury
- Lifetime major neurologic syndromes such as stroke, epilepsy, or brain tumor
- Lifetime major cardiovascular conditions such as heart attack or heart failure
- Current substance use disorder
- Current major psychiatric disorders such as major depressive disorder or bipolar disorder
- Current vision or hearing impairment interfering with testing
- Any electronic or metallic implants in the skull or brain
- Current use of medications known to affect HD-tDCS response
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Texas Southwestern Medical Center
Dallas, Texas, United States, 75390
Actively Recruiting
Research Team
H
Hannah Cabrera, MCRC
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
DIAGNOSTIC
Number of Arms
3
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