Patient Blood Management in Cardiac Surgical Patients: the ICARUS-2 Study

What this Trial Is About

Researchers are studying patients scheduled for elective cardiac surgery to improve management of iron deficiency and reduce the need for blood transfusions during and after surgery. This observational study focuses on optimizing hemoglobin levels by correcting low iron levels prior to surgery. The goal is to enhance recovery from blood loss related to cardiac surgery, supported by current patient blood management programs. Participants with low iron or iron deficiency will receive intravenous iron treatment at least two weeks before their scheduled surgery, along with vitamin B12 injections and oral folic acid. The study compares groups of patients treated early with iron supplementation, those treated shortly before surgery, and those with unknown iron status who did not receive treatment. This approach aims to assess how earlier correction of iron deficiency affects outcomes. During the study, researchers will monitor the number of blood transfusions given within seven days after surgery, hemoglobin values, length of stay in intensive care and hospital, mortality rates, and costs related to iron deficiency treatment and blood product use. Data collection will continue for about two years. Participants will have blood tests and receive treatments as part of standard clinical care while researchers observe and record relevant health outcomes.

Patient Blood Management in Patients Scheduled for Cardiac Surgery