Actively Recruiting

Phase Not Applicable
Age: 65Years +
All Genders
NCT05842928

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy

Led by Ludwig-Maximilians - University of Munich · Updated on 2025-05-04

352

Participants Needed

3

Research Sites

183 weeks

Total Duration

On this page

Sponsors

L

Ludwig-Maximilians - University of Munich

Lead Sponsor

B

Bielefeld University

Collaborating Sponsor

AI-Summary

What this Trial Is About

The PARTNER study is a multicentre, two-arm, pragmatic cluster-randomised trial evaluating the impact of a focused and patient-centred cooperation between general practitioners (GPs) and community pharmacists (PARTNER intervention) on reductions in the use of psychotropic, sedative and anticholinergic potentially inappropriate medication (PSA-PIM) compared to a control intervention. The PARTNER intervention comprises (1) education for health care professionals, (2) an interprofessional workshop and case conference, (3) a pharmacy visit with brown bag/medication review and patient empowerment, (4) GP practice visit with shared decision making. The control intervention only comprises a pharmacy visit with brown bag review.

CONDITIONS

Official Title

Patient-centred Deprescribing of Psychotropic, Sedative and Anticholinergic Medication in Elderly Patients With Polypharmacy

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 65 years or older
  • Patient is capable of giving consent
  • GP contact in the quarter prior to inclusion
  • Current use of 5 or more drugs, including at least 1 psychotropic, sedative, or anticholinergic medication with treatment duration of 6 months or more
  • Willingness to select a regular pharmacy for the study period
  • Consent to data exchange between GP and community pharmacy
Not Eligible

You will not qualify if you...

  • Terminal illness with life expectancy less than 6 months
  • Current treatment of pain associated with cancer
  • Serious physical illness or mental distress making participation impossible (as assessed by GP)
  • Psychiatric illness or addiction making participation impossible (as assessed by GP)
  • Unable to meet study requirements such as participating in questionnaires or visits
  • Current participation in other research projects on medication safety or geriatric medicine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 3 locations

1

University of Bielefeld

Bielefeld, Germany, 33615

Not Yet Recruiting

2

University Hospital, LMU Munich

Munich, Germany, 80336

Actively Recruiting

3

Witten/Herdecke University

Witten, Germany, 58448

Not Yet Recruiting

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Research Team

T

Tobias Dreischulte, Prof. Dr.

CONTACT

A

Annette Haerdtlein

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

2

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