Actively Recruiting
Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
Led by University of California, San Francisco · Updated on 2026-03-09
250
Participants Needed
1
Research Sites
294 weeks
Total Duration
On this page
Sponsors
U
University of California, San Francisco
Lead Sponsor
U
United States Department of Defense
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial explores and implements methods to improve informed decision making (IDM) regarding precision oncology tests amongst veterans with prostate cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced). Precision oncology, the use of germline genetic testing and tumor-based molecular assays to inform cancer care, has become an important aspect of evidence-based care for men with advanced prostate cancer. Veterans with metastatic castrate-resistant prostate cancer may not be carrying out IDM due to unmet decisional needs. An informed decision is a choice based on complete and accurate information. The information gained from this study will help researchers develop a decision support intervention (DSI) and implement the intervention. A DSI may serve as a valuable tool to reduce ongoing racial disparities in genetic testing and encourage enrollment to precision oncology trials.
CONDITIONS
Official Title
Patient Decision-making About Precision Oncology in Veterans With Advanced Prostate Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Able to understand and comply with study procedures for the entire study length
- Able and willing to sign a written informed consent document
- Able to speak, read, and understand English
- Documentation of locally advanced (pelvic lymph node-positive), metastatic, or castration-resistant prostate cancer
- Scheduled to attend a hematology/oncology appointment (in person or remote) where germline testing, somatic tumor testing, or targeted therapy will be discussed
- Caregivers: Identified by a patient as involved in their care and willing to join interviews
- Providers: Hematology/oncology or genetics providers who have discussed relevant testing or therapy with eligible patients in the past 90 days (or as specified)
- For later stages, participants must have completed prior study stages and testing as specified
You will not qualify if you...
- For patients undergoing genetic testing, if test results have already been disclosed, they are not eligible
- Prior receipt of germline testing
- Prior participation in Stage 1 for germline testing
- Caregivers and providers who do not meet inclusion criteria
- Participants who do not meet the specified inclusion criteria in each study stage
AI-Screening
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Trial Site Locations
Total: 1 location
1
San Francisco Veterans Affairs Medical Center
San Francisco, California, United States, 94121
Actively Recruiting
Research Team
U
UCSF Genitourinary Medical Oncology Recruitment
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
HEALTH_SERVICES_RESEARCH
Number of Arms
2
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